14. Management of locally advanced nonsmall cell lung cancer 260 M. Edelmann, R.M. Huber 15. Chemotherapy in advanced nonsmall cell lung cancer 271 E. Quoix 16. Targeted therapy in nonsmall cell lung cancer 284 D.F. Heigener, M. Reck, U. Gatzemeier 17. Treatment of limited disease-small cell lung cancer 299 D. De Ruysscher, C. Pöttgen, H.J.M. Groen, S.M. Bentzen 18. Management of extensive disease-small cell lung cancer 310 P.E. Postmus, E.F. Smit 19. Malignant pleural disease in primary lung cancer 318 E. Mishra, H.E. Davies, Y.C.G. Lee 20. Endobronchial management of central cancers 336 F.J.F. Herth 21. Epidemiology of lung cancer and mesothelioma 349 J.M. Samet, A.J. Alberg, J.G. Ford 22. Diagnosis and staging of mesothelioma 392 A. Scherpereel 23. Surgery and multimodality treatment for malignant pleural 407 mesothelioma W. Weder, I. Opitz, R. Stahel 24. Systemic treatment of malignant mesothelioma 419 R.M. Rudd Statements of interest 435 Contents MON 44.qxd 03/06/2009 12:57 Page 2