Contents Preface v Guest Editors vii Introduction: Supporting tobacco cessation – from health policy to xi health system reorientation and patient care List of abbreviations xvi The challenging changing landscape of the tobacco epidemic 1. Tobacco is still the most important preventable cause of 1 respiratory diseases Linnea Hedman, David Ashley, Filippos Filippidis, Tanzer Gezer and Charlotta Pisinger 2. Understanding nicotine addiction and the health effects of nicotine use 18 Sakire Pogun and Ayse Rodopman Arman 3. E-cigarettes, heated tobacco and other novel nicotine-containing 33 products: a help to smokers or a public health threat? Charlotta Pisinger, Paraskevi Katsaounou, Sofia Belo Ravara and Jørgen Vestbo Treatment of tobacco dependence 4. Practical guidance on the use of motivational interviewing to 56 support behaviour change Lynne Johnston, Charlotte Hilton and Frankie Dempsey 5. Behaviour counselling and psychosocial interventions. The role 76 of patient involvement Cristina Martínez, Sotiria Schoretsaniti, Alex Bobak and Monica Fletcher 6. Evidence of the effectiveness and safety of first-line smoking 97 cessation pharmacotherapy Evangelia Liakoni and Neal L. Benowitz 7. Optimising health systems to deliver tobacco-dependence treatment 118 Keir E. Lewis, Sofia Belo Ravara, Sophia Papadakis, Darush Attar-Zadeh, Joan Hanafin, Luke Clancy, Mette Rasmussen, Paraskevi Katsaounou and Dongbo Fu ERS monograph Supporting Tobacco Cessation Number 90 January 2021