CONTENTS Preface a Introduction b 1. Indications, patient selection and timing of referral for lung transplantation 1 A.R. Glanville, M. Estenne 2. The management of patients awaiting lung transplantation 16 J.J. Egan 3. Medical treatment of pulmonary arterial hypertension 31 J-L. Vachiéry 4. Lung volume reduction surgery 40 W. Weder 5. Pulmonary thromboendarterectomy 47 E. Mayer, T. Kramm, S. Guth, K.F. Kreimer, B. Eberle, H. Oelert 6. Organ shortage and the organisation of organ allocation 62 B. Miranda, J. Cañón, N. Cuende, M.T. Naya, G. Garrido, E. Fernandez-Zincke 7. Donor selection and management 78 P.A. Corris 8. Lung preservation 86 D. Van Raemdonck, S. Steen 9. Operative techniques 98 H. Treede, H. Reichenspurner, W. Weder 10. Immunosuppressive therapy after human lung transplantation 105 C. Knoop, A. Haverich, S. Fisher 11. Perioperative lung transplant management 130 G. Snell, W. Klepetko 12. Lung pathology 143 S. Stewart 13. Post-transplant bronchiolitis obliterans 158 A. Boehler, M. Estenne The European Respiratory Monograph Number 26 September 2003 Contents MON 26.qxd 11/08/2003 14:16 Page 1