PUBLISHED BY EUROPEAN RESPIRATORY SOCIETY CHIEF EDITORS Anita K. Simonds (London, UK) Wilfried de Backer (Antwerp, Belgium) AUTHORS ERS STAFF Matt Broadhead, Jonathan Hansen, Sarah Hill, Sharon Mitchell, Victoria Morton, Elin Reeves, Rachel White © 2012 European Respiratory Society Design by Claire Turner and Lee Dodd, ERS Typeset in China by Charlesworth Group Printed in the UK Page Bros (Norwich) Ltd Indexed by Merrall-Ross International Ltd All material is copyright to the European Respiratory Society. It may not be reproduced in any way including electronically without the express permission of the society. CONTACT AND PERMISSIONS REQUESTS: European Respiratory Society, 442 Glossop Road, Sheffield, S10 2PX, UK Tel: 44 114 2672860 Fax: 44 114 2665064 e-mail: info@ersj.org.uk ISBN 978-1-84984-023-1 Stefan Andreas Chiara Baglioni Ferrán Barbé Maria R. Bonsignore An Boudewiyns Gary Cohen Viliam Donic Athanasios Kaditis Miriam Katz-Salomon Brian D. Kent Eric Konofal Michel Lecendreux Patrick Levy Marie Marklund Juan Fernando Masa Walter T. McNicholas Josep M. Montserrat Mary J. Morrell Gimbada B. Mwenge Arie Oksenberg Paolo Palange Dirk Pevernagie Winfried Randerath Dieter Riemann Renata L. Riha Daniel Rodenstein Silke Ryan Zoltan Tomori Ha Trang Johan Verbraecken Stijn Verhulst Maria Pia Villa