Chest pain 59 Matthew Hind Physical examination 61 Martyn R. Partridge Chapter 3 – Pulmonary function testing Static and dynamic lung volumes 66 Riccardo Pellegrino and Andrea Antonelli Respiratory mechanics 72 Daniel Navajas and Ramon Farré Gas transfer: TLCO and TLNO 77 J. Mike Hughes Control of ventilation 82 Brian J. Whipp and Susan A. Ward Arterial blood gas assessment 87 Paolo Palange, Alessandro Maria Ferazza and Josep Roca Exercise testing 94 Paolo Palange and Paolo Onorati Bronchial provocation testing 99 Kai-Håkon Carlsen Sputum and exhaled breath analysis 103 Patrizia Pignatti, Andrea Zanini, Sabrina Della Patrona, Federico Gumiero, Francesca Cherubino and Antonio Spanevello