Extrapulmonary manifestations of CF 410 Anne Munck, Manfred Ballmann and Anders Lindblad Emerging treatment strategies in CF 421 Melinda Solomon and Felix Ratjen Prognosis, management and indications for lung transplantation in CF 427 Helen Spencer and Andrew Bush Chapter 12 – Congenital malformations Airway malformations 435 Ernst Eber and Andreas Pfleger Thoracic malformations 445 Ashok Daya Ram, Jennifer Calvert and Sailesh Kotecha Vascular malformations 452 Oliviero Sacco, Serena Panigada, Nicoletta Solari, Elena Ribera, Chiara Gardella, Silvia Rosina, Michele Ghezzi and Francesca Rizzo Chapter 13 – Bronchopulmonary dysplasia and chronic lung disease Aetiology, pathogenesis, prevention and evidence-based 461 medical management Robert I. Ross-Russell Nutritional care 466 Kajsa Bohlin Neurodevelopmental assessment and outcomes 469 Charles C. Roehr, Lex W. Doyle and Peter G. Davis Long-term respiratory outcomes 472 Manuela Fortuna, Marco Filippone and Eugenio Baraldi Chapter 14 – Pleural, mediastinal and chest wall diseases Pleural effusion, chylothorax, haemothorax and mediastinitis 477 Juan Antón-Pacheco, Carmen Lucas-Paredes and Antonio Martinez-Gimeno Pneumothorax and pneumomediastinum 485 Nicolaus Schwerk, Folke Brinkmann and Hartmut Grasemann