Neuromuscular disorders 492 Anita K. Simonds Chest wall disorders 497 Daniel Trachsel, Carol-Claudius Hasler and Jürg Hammer Chapter 15 – Sleep-related disorders Physiology and pathophysiology of sleep 503 Sedat Oktem and Refika Ersu OSAS and upper respiratory airway resistance syndrome 514 Maria Pia Villa and Silvia Miano Central sleep apnoea and hypoventilation syndromes 521 Malin Rohdin and Hugo Lagercrantz Impact of obesity on respiratory function 528 Andrea Bon, Martina Tubaro and Mario Canciani Chapter 16 – Lung injury and respiratory failure Lung injury 533 Andreas Schibler Acute and chronic respiratory failure 538 Robert I. Ross-Russell and Colin Wallis Home oxygen therapy, invasive ventilation and NIV, and home 545 ventilatory support Brigitte Fauroux, Adriana Ramirez and Sonia Khirani Chapter 17 – Other respiratory diseases Primary ciliary dyskinesia 551 Deborah Snijders, Serena Calgaro, Massimo Pifferi, Giovanni Rossi and Angelo Barbato Gastro-oesophageal reflux-associated lung disease and 559 aspiration syndrome Osvaldo Borelli, Efstratios Saliakellis, Fernanda Cristofori and Keith J. Lindley