Anne-Marie C.
and Virginie
Lung cancer still represents one of the most frequent solid tumours with the highest
tumour-associated mortality and increasing global incidence rates.
Relevant changes have been seen in epidemiology and there have been substantial
improvements in all disciplines of lung cancer treatment. However, the picture of lung
cancer treatment has become quite complex, and treatment strategies are moving more and
more from global treatment algorithms to individualised treatment.
Standardised and adequate histological, as well as molecular classification (as it is reflected
in the recommendations for ADC classification), have become crucial in order to give the
individual patient the chance of optimal treatment.
As well as relevant steps in surgery and radiotherapy, new impressive opportunities in
systemic treatment have opened up through the identification of treatable oncogenic driver
alterations and the appropriate targeted therapies. Furthermore, in 2015, after decades of
negative trials, we are experiencing a fascinating phase of immunotherapy with a completely
new class of agents.
Of all the solid tumours, lung cancer has really demonstrated rapid and substantial
progress in treatment efficacy based on major progress in diagnostics. Therefore, it is of
paramount importance that the pulmonologist as key member of the interdisciplinary team
is familiar with the current state of the art in lung cancer care.
We hope that this issue will be of interest to all researchers, clinicians and surgeons in the
respiratory field and that it will help to improve understanding about lung cancer,
answering all the questions encountered in everyday practice.
Copyright ©ERS 2015. Print ISBN: 978-1-84984-061-3. Online ISBN: 978-1-84984-062-0. Print ISSN: 2312-508X. Online ISSN: 2312-5098.
Correspondence: Dept of Thoracic Oncology, Lung Clinic, Airway Research Center North (ARCN), Woehrendamm 80, Grosshansdorf 22927,
Germany. E-mail:
of Thoracic Oncology, Lung Clinic, Airway Research Center North (ARCN), Grosshansdorf, Germany.
University Medical Centre, Maastricht, The Netherlands.
de Pneumologie, CHRU Hôpital Jean Minjoz, Besançon cedex, France.
de Franche-Comté, Besançon, France.
ERS Monogr 2015; 68: xiii DOI: 10.1183/2312508X.10003615 xiii
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