The Challenge of Tuberculosis in the 21st Century Edited by Alberto L. García-Basteiro, Füsun Öner Eyüboğlu and Molebogeng X. Rangaka Editor in Chief Peter M.A. Calverley This book is one in a series of ERS Monographs. Each individual issue provides a comprehensive overview of one specific clinical area of respiratory health, communicating information about the most advanced techniques and systems required for its investigation. It provides factual and useful scientific detail, drawing on specific case studies and looking into the diagnosis and management of individual patients. Previously published titles in this series are listed at the back of this Monograph. ERS Monographs are available online at books.ersjournals.com and print copies are available from www.ersbookshop.com