ABPA allergic bronchopulmonary aspergillosis ACQ Asthma Control Questionnaire BAL bronchoalveolar lavage BMI body mass index COPD chronic obstructive pulmonary disease CRTH2 chemoattractant receptor homologous molecule expressed on Th2 lymphocytes CT computed tomography FeNO exhaled nitric oxide fraction FEV1 forced expiratory volume in 1 s FRC functional residual capacity FVC forced vital capacity GINA Global Initiative for Asthma GM-CSF granulocyte-macrophage colony-stimulating factor ICS inhaled corticosteroid ICU intensive care unit IFN interferon Ig immunoglobulin IL interleukin ILC innate lymphoid cell LABA long-acting β-agonist LAMA long-acting muscarinic antagonist MMP matrix metalloproteinase MRI magnetic resonance imaging NSAID non-steroidal anti-inflammatory drug OCS oral corticosteroid SARP Severe Asthma Research Program TGF transforming growth factor TNF tumour necrosis factor TSLP thymic stromal lymphopoietin U-BIOPRED Unbiased Biomarkers in the Prediction of Respiratory Disease VCD vocal cord dysfunction VOC volatile organic compound List of abbreviations