CONTENTS Preface a Introduction b 1. Genetic and acquired risk factors of venous thromboembolism 1 R. Verhaeghe, P. de Moerloose, J.C. Eikenboom, K. Peerlinck, A. Perrier, J. Vermylen, M.M. Samama, and the other participants of the working group "Management of pulmonary embolism" 2. Diagnostic aspects of pulmonary embolism 15 R. Verhaeghe, P. de Moerloose, I. Greer, M.V. Huisman, R. Hustinx, M. Monreal, L. Mortelmans, A. Perrier, M. Remy-Jardin, A. Torbicki, E.J.R. van Beek, and the other participants of the working group "Management of pulmonary embolism" 3. Therapeutic aspects of pulmonary embolism 25 R. Verhaeghe, G. Agnelli, C. Becattini, H. Decousus, G. Simonneau, E.J.R. van Beek, and the other participants of the working group "Management of pulmonary embolism" 4. Pulmonary arterial hypertension: genetics, reversibility testing and 33 follow-up M. Delcroix, N.W. Morrell, M. Abramowicz, O. Sitbon, A. Boonstra, N. Galie, E. Grünig, P. Hervé, R.C. Trembath, A.J. Peacock, M.M. Hoeper, and the other participants of the working group "Pulmonary arterial hypertension" 5. Pulmonary arterial hypertension: current therapies 57 M. Delcroix, W. Budts, P.A. Corris, W. Daenen, M. Gewillig, R. Naeije, H. Olschewski, J. Pepke-Zaba, W. Seeger, J-L. Vachiéry, D. Van Raemdonck, C.D. Vizza, and the other participants of the working group "Pulmonary arterial hypertension" 6. Pulmonary hypertension: future therapies 84 M. Delcroix, P. Dorfmüller, M.R. MacLean, J.A. Barbera, M.M. Hoeper, G. Ghofrani, S. Adnot, S. Eddahibi, S. Janssens, A.J. Peacock, J. Pepke-Zaba, D. Vizza, and the other participants of the working group "Pulmonary arterial hypertension" 7. Imaging of pulmonary embolism: an overview 110 E.J.R. van Beek, A.R. Moody, M. Oudkerk 8. Spiral computed tomography angiography of pulmonary embolism 124 M. Remy-Jardin, B. Ghaye, J. Remy The European Respiratory Monograph Number 27 January 2004 Contents MON 27.qxd 18/11/2003 10:40 Page 1