Contents Preface v Guest Editors vi Introduction ix List of abbreviations xiv 1. Multidisciplinary approach to systemic diseases: benefits for diagnosis 1 and management of complex disorders Fabrizio Luppi, Paola Faverio and Wim A. Wuyts 2. Pulmonary function tests in multisystem disorders: prejudices 14 and pitfalls Claudia Valenzuela and Athol U. Wells 3. Quantitative CT analysis in ILD and the use of artificial intelligence 27 on imaging of ILD Lucio Calandriello, Tahreema Matin, Helmut Prosch and Joseph Jacob Connective tissue diseases 4. Rheumatoid arthritis 44 John A. Mackintosh, Anna Stainer, Laurens J. De Sadeleer, Carmel Stock, Wim A. Wuyts and Elisabetta A. Renzoni 5. Inflammatory myopathies 68 Vincent Cottin, Thomas Barba, Sabine Mainbourg, Mouhamad Nasser, Claudia Valenzuela and Jean-Christophe Lega 6. Systemic sclerosis 90 Athol U. Wells 7. Systemic lupus erythematosus, Sjögren syndrome and mixed 106 connective tissue disease Katerina M. Antoniou, Eirini Vasarmidi, Athina Trachalaki, Eleni Bibaki and Bruno Crestani 8. Antiphospholipid syndrome 124 Shaney L. Barratt, John D. Pauling and Nazia Chaudhuri 9. Interstitial pneumonia with autoimmune features 140 Alison M. DeDent and Aryeh Fischer ERS monograph Pulmonary Manifestations of Systemic Diseases Number 86 December 2019