ERS | monograph Guest Editors David J. Jackson David J. Jackson is an Associate Professor of Respiratory Medicine at King’s College London (London, UK) and Clinical Director of Guy’s Severe Asthma Centre, Guy’s & St Thomas’ NHS Trust (London, UK), a regional unit for severe asthma, eosinophilic granulomatosis with polyantiitis (EGPA) and other eosinophilic lung diseases, which receives approximately 1000 referrals per year from a network of hospitals across London and South-East England. Following an MSc in allergy and a PhD investigating the mechanisms of virus-induced asthma exacerbations at Imperial College London (London, UK), David’s more recent research has focused on the clinical aspects of severe asthma care, including investigating subphenotypes of asthma and EGPA made evident by their differential response to targeted biological therapies. David is on the steering committee of the International Severe Asthma Registry (ISAR), is an assembly member of the Global Initiative for Asthma (GINA), and is on the asthma specialist advisory group of the British Thoracic Society (BTS). He holds senior editorial positions at several journals, including Chest, the European Respiratory Review and Allergy,and has published original research in Nature Medicine, Science Translational Medicine, JAMA Internal Medicine and Lancet Respiratory Medicine, as well as several other respiratory- and allergy-related journals. Michael E. Wechsler Michael E. Wechsler is Professor of Medicine in the Division of Pulmonary, Critical Care and Sleep Medicine at National Jewish Health (NJH) in Denver (CO, USA), Director of the NJH/ Cohen Family Asthma Institute (Denver) and Associate Vice President for Innovation and Industry Relations at NJH. Michael received AB and MMSc degrees from Harvard University (Boston, MA, USA) and an MD degree from McGill University (Montreal, QC, Canada). He completed medical training at Beth Israel Hospital (Boston), and as part of the Harvard Combined Pulmonary and Critical Care Fellowship Training Program. Copyright ©ERS 2022. Print ISBN: 978-1-84984-142-9. Online ISBN: 978-1-84984-143-6. Print ISSN: 2312-508X. Online ISSN: 2312-5098. vi https://doi.org/10.1183/2312508X.10017721