Contents
Preface vii
Guest Editors ix
Introduction xi
List of abbreviations xiv
1. The patients’ perspective on living with COPD and their priorities for 1
future research and care
Michaela Senek, Artur Badyda, Simona Barbaglia, Andy Barker, Piotr Dąbrowiecki,
Cristina Jacomelli, Tessa Jelen, Valeria Ramiconi, Isabel Saraiva, Knut Magne Skaar
and Courtney Coleman
2. COPD as the new millennium began 16
Peter M.A. Calverley
3. Defining COPD in the 21st century 30
David M.G. Halpin
4. A new understanding of the natural history of COPD 45
Alvar Agustí and Rosa Faner
5. The new epidemiology of COPD 63
Muhammad Ijlal Khan, Malik M. Khurram S. Khan and David M. Mannino
6. Cardiac comorbidity and COPD: chance or consequence? 81
Tetsuro Maeda and Mark T. Dransfield
7. Mechanisms and medicators of disease 100
Justine V. Devulder and Louise E. Donnelly
8. The microbiome and COPD 118
Pei Yee Tiew and Sanjay H. Chotirmall
9. Chronic bronchitis revisited 135
James P. Allinson
10. Eosinophils and COPD 149
Augusta Beech and Dave Singh
ERS monograph
COPD in the 21st Century Number 103
March 2024
Preface vii
Guest Editors ix
Introduction xi
List of abbreviations xiv
1. The patients’ perspective on living with COPD and their priorities for 1
future research and care
Michaela Senek, Artur Badyda, Simona Barbaglia, Andy Barker, Piotr Dąbrowiecki,
Cristina Jacomelli, Tessa Jelen, Valeria Ramiconi, Isabel Saraiva, Knut Magne Skaar
and Courtney Coleman
2. COPD as the new millennium began 16
Peter M.A. Calverley
3. Defining COPD in the 21st century 30
David M.G. Halpin
4. A new understanding of the natural history of COPD 45
Alvar Agustí and Rosa Faner
5. The new epidemiology of COPD 63
Muhammad Ijlal Khan, Malik M. Khurram S. Khan and David M. Mannino
6. Cardiac comorbidity and COPD: chance or consequence? 81
Tetsuro Maeda and Mark T. Dransfield
7. Mechanisms and medicators of disease 100
Justine V. Devulder and Louise E. Donnelly
8. The microbiome and COPD 118
Pei Yee Tiew and Sanjay H. Chotirmall
9. Chronic bronchitis revisited 135
James P. Allinson
10. Eosinophils and COPD 149
Augusta Beech and Dave Singh
ERS monograph
COPD in the 21st Century Number 103
March 2024