12. Non-tuberculous mycobacterial lung disease and COPD 172 Chun-Ta Huang, Meng-Rui Lee, Chin-Chung Shu, Jann-Yuan Wang and Pan-Chyr Yang 13. Pneumonia or exacerbation of COPD? 185 Diego Jose Maselli and Marcos I. Restrepo 14. Prophylactic antibiotics 197 David J. Serisier† 15. Inhaled medication: which device for which patient? 213 Mario Cazzola and Paola Rogliani 16. The importance of physical activity 224 Daniel Langer, Heleen Demeyer, Thierry Troosters and Rik Gosselink 17. How to assess the benefits of pulmonary rehabilitation 240 Carlos Augusto Camillo, Christian Osadnik, Wim Janssens and Thierry Troosters 18. Measurable aspects of health status in clinical practice 256 Jan H. Vercoulen, A. Rogier Donders and Jeannette B. Peters 19. The role of telemedicine 269 Annemarie L. Lee and Roger S. Goldstein 20. The challenge of palliative care 297 Laura-Jane Smith and Jennifer K. Quint