Jean-Louis Pépin Jean-Louis Pépin is Professor of Clinical Physiology at the University Grenoble-Alpes (UGA) (Grenoble, France). He is Head of the Clinic of Physiology, Sleep and Exercise at Grenoble University Hospital (CHUGA) (Grenoble, France), Director of the HP2 Laboratory (INSERM U1042, UGA Hypoxia Pathophysiology), and vice-Dean of the Faculty of Medicine in charge of research and Scientific Director of clinical research at CHUGA. Jean-Louis is also the director of the UGA Chair of Excellence in e-health and integrated care and the Artificial intelligence Chair “Trajectories Medicine” (2018–2021). Jean-Louis graduated as: MD in 1987 at the University of Montpellier (Montpellier, France) MSc in 1990, in biophysiology at the University Claude Bernard, Lyon, France and PhD in 1998, in cardiovascular adaptations induced by chronic hypoxia, at the University Joseph Fourier, Grenoble. In 1999, he was Visiting Professor at the Laboratory of Pulmonary Physiology of Harvard University (Boston, MA, USA). He achieved European certification in sleep medicine in 2013. Jean-Louis’ interests include clinical and translational research on the cardiovascular consequences of chronic and intermittent hypoxia, sleep apnoea, COPD and chronic respiratory failure. Jean-Louis runs the French National Prospective Registry of Sleep Apnea (RESAS), which has 120000 subjects, and is involved in the European Sleep Apnea Database (ESADA). He has participated in several European and US thoracic society task forces, and is the former President of the French Sleep Research and Medicine Society. He has experience in innovation (he has 10 patents), in clinical trials and in industrial partnerships. He was the principle investigator of OPTISAS, a national telemedicine trial on sleep apnoea, and on LIFE, a transdisciplinary research program involving 70 researchers on evidence-based societal and environmental control of chronic diseases, funded by UGA-IDEX. He has been funded by EIT-Health for several European Union projects and is ranked third highest expert worldwide in the field of sleep apnea by Expertscape. Jean-Louis is an Associate Editor of Thorax, is author/co-author of 450 scientific publications and has an H-index of 58. https://doi.org/10.1183/2312508X.10005320 ix