ERS | monograph Guest Editors Pavel Strnad Pavel Strnad is an Associate Professor and Senior Physician at the University Hospital Aachen, Aachen, Germany. He received his medical and research training at the University of Mainz, Mainz, Germany, and at Stanford University, Stanford, CA, USA. His research interests include clinical and experimental hepatology, with a focus on intermediate filaments, iron metabolism and AATD. In 2016, he was named a Rising Star by United European Gastroenterology (UEG). Pavel Strnad currently leads a European initiative for the study of AATD-associated liver disease. He is a member of the editorial boards of several journals, including Gastroenterology, PLoS ONE and Digestive Diseases and Sciences. He is also reviewer of rare diseases for the the European Association for the Study of the Liver. Mark L. Brantly Mark L. Brantly is a Professor of Medicine and Chief of Molecular Genetics and Microbiology in the Division of Pulmonary, Critical Care and Sleep Medicine at the University of Florida College of Medicine in Gainesville (FL, USA), where he is also the Alpha-1 Foundation Research Professor. Mark L. Brantly earned his medical degree from the University of Florida College of Medicine. He completed a residency in internal medicine at Eastern Virginia Medical School in Norfolk (VA, USA), where he was also Chief Medical Resident, and a research fellowship in pulmonary disease at the National Institutes of Health (NIH) in Bethesda (MD, USA). Mark L. Brantly was a senior scientist at NIH for 13 years in the National Institute of Child Health and Human Development (NICHD) Human Genetics Branch and the National Heart, Lung, and Blood Institute (NHLBI) Pulmonary Branch. Mark L. Brantly’s clinical and research interests include AATD and lung inflammation and the molecular basis of lung and Copyright ©ERS 2019. Print ISBN: 978-1-84984-108-5. Online ISBN: 978-1-84984-109-2. Print ISSN: 2312-508X. Online ISSN: 2312-5098. https://doi.org/10.1183/2312508X.10026719 vii