Severe Asthma Edited by Kian Fan Chung, Elliot Israel and Peter G. Gibson Pantone 200 CMJN (darker) Cyan 0 Magenta 100 Yellow 70 Black 14 Pantone 647 CMJN Cyan 100 Magenta 56 Yellow 0 Black 24 Pantone PASTEL 9081 CMJN Cyan 0 Magenta 0 Yellow 6 Black 8 ERS monograph Severe Asthma ERS monograph 84 ERS monograph Print ISSN: 2312-508X Online ISSN: 2312-5098 Print ISBN: 978-1-84984-103-0 Online ISBN: 978-1-84984-104-7 June 2019 €60.00 Pantone 200 CMJN (darker) Cyan 0 Magenta 100 Yellow 70 Black 14 Pantone 647 CMJN Cyan 100 Magenta 56 Yellow 0 Black 24 Pantone PASTEL 9081 CMJN Cyan 0 Magenta 0 Ythe6 ellow Black 8 Severe asthma is a form of asthma that responds poorly to currently available medication, and its patients represent those with the greatest unmet needs. In last 10 years, substantial progress has been made in terms of understanding some of the mechanisms that drive severe asthma there have also been concomitant advances in the recognition of specific molecular phenotypes. This ERS Monograph covers all aspects of severe asthma – epidemiology, diagnosis, mechanisms, treatment and management – but has a particular focus on recent understanding of mechanistic heterogeneity based on an analytic approach using various ‘omics platforms applied to clinically well-defined asthma cohorts. How these advances have led to improved management targets is also emphasised. This book brings together the clinical and scientific expertise of those from around the world who are collaborating to solve the problem of severe asthma.
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