PUBLISHED BY THE EUROPEAN RESPIRATORY SOCIETY EDITORS Konrad E. Bloch with Paolo Palange and Anita K. Simonds AUTHORS AND REVIEWERS ERS STAFF Matt Broadhead, Jonathan Hansen, Julie-Lyn Noel, Elin Reeves, David Sadler, Victoria Smith © 2012 European Respiratory Society Design by Claire Turner and Lee Dodd, ERS Typeset in China by Charlesworth Group Printed in the UK by Charlesworth Press All material is copyright to the European Respiratory Society. It may not be reproduced in any way including electronically without the express permission of the society. CONTACT, PERMISSIONS AND SALES REQUESTS: European Respiratory Society, 442 Glossop Road, Sheffield, S10 2PX, UK Tel: 44 114 2672860 Fax: 44 114 2665064 e-mail: info@ersj.org.uk ISBN 978-1-84984-029-3 Stefan Andreas Konrad E. Bloch Thomas Brack Richard Costello Mina Gaga Ildikó Horváth Kostas Kostikas Christian M. Lo Cascio Robert Loddenkemper Stelios Loukides Paolo Palange Anita K. Simonds Frank Smeenk Robin Stevenson Robert Thurnheer Eleftherios Zervas