Alexandre Demoule Alexandre Demoule is professor of intensive care medicine at the Pierre and Marie Curie University Medical Centre in Paris (France). He is the director of the medical ICU, the step-down unit and the weaning centre within the Dept of Pneumology and Intensive Care Medicine, La Pitié-Salpêtrière hospital in Paris. He was trained in pneumology and physiology at the Pierre and Marie Curie University under the supervision of Thomas Similowski and in intensive care medicine at Paris-Est University in Créteil, where he was also a research fellow (2001–2002) in mechanical ventilation with Laurent Brochard. From 2003 to 2006, he was a PhD student in respiratory physiology at the Pierre and Marie Curie University. During the PhD programme he spent 1.5 years at the Meakins-Christie Laboratories, McGill University (Montreal, QC, Canada), under the supervision of Basil Petrof. His main research field is patient–ventilator interactions. It involves specific research topics such as brain–ventilator interactions, the impact of mechanical ventilation on respiratory sensations and comfort, and respiratory muscle dysfunction in mechanically ventilated patients. He also conducts clinical studies on noninvasive mechanical ventilation in acute respiratory failure and on new modes of mechanical ventilation. His research projects are conducted within UMR_S 1158, a joint research unit between Pierre and Marie Curie University and the French National Institute of Health and Medical Research (Inserm). Alexandre Demoule is the chair of the annual meeting of the French Intensive Care Society. He has organised several conferences on mechanical ventilation, is co-author of guidelines in the field of intensive care medicine and serves as an invited speaker at international conferences. Wolfram Windisch Wolfram Windisch is the medical director of the Dept of Pneumology and Critical Care Medicine, Clinic of Cologne (Cologne, Germany), and holds the professorial chair for Pneumology at the University of Witten/Herdecke (Cologne). His department is specifically dedicated to the acute and chronic treatment of respiratory failure, invasive and noninvasive mechanical ventilation, extracorporeal lung assist, weaning from mechanical ventilation and sleep medicine. In addition, his other main focuses are COPD/asthma, thoracic oncology, interstitial lung diseases, infectious diseases and cystic fibrosis. His research interests include respiratory physiology, all aspects of mechanical ventilation, monitoring of respiratory function in the acute and viii
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